张斌 博士
生物工程专业：硕士生导师
生物与医药专业（生物工程领域）：硕士生导师
个人简介
华东理工大学生物工程学院，特聘副研究员。入选上海市“超级博士后”激励计划、上海市科技启明星“扬帆计划”。研究紧扣国家“双碳”目标发展战略，以产业化应用为导向，聚焦于非粮木质纤维素生物质原料的生物转化、微生物油脂和单细胞蛋白等产品的合成生物学研究等。累计发表SCI论文三十余篇，申请发明专利十余项（授权5项），作为课题负责人获国家自然科学青年基金、国家重点研发计划子课题、博士后面上项目、企业横向课题等十余项科研基金资助。
教育和工作经历
2012.6-2016.6，北京化工大学，生物工程，本科
2016.9-2018.12，广西大学，生物工程，硕士
2019.9-2022.7，华东理工大学，生物工程，工学博士
2022.8-2024.8，华东理工大学化学工程与技术博士后科研流动站，博士后
2024.9-至今，华东理工大学生物工程学院，特聘副研究员
研究方向
生物炼制与合成生物学
1.非粮木质纤维素生物质的低碳生物炼制过程。
2.超级生物炼制微生物的发现、进化及代谢工程改造，合成关键生物基产品。
3.碳中和生物炼制工程及其计算机流程模拟和生命周期分析。
主持的科研项目：
(1) 国家重点研发计划子课题，2023YFA0914400，2024-2028，120万元，主持。
(2) 国家自然科学基金青年基金，32301269，2024-2026，30万元，主持。
(3) 中国博士后科学基金面上资助，2023M741175，2024-2025，8万元，主持。
(4) 上海市科技启明星（扬帆专项），2023YF1409900，2023-2025，20万元，主持。
(5) 企业横向课题，“高手性乳酸稳定生产工业菌株开发”，2022-2024，50万元，主持。
(6) 企业横向课题，“农作物秸秆用于生产油脂和蛋白产品的菌种和工艺开发”，2023-2025，150万元，主持。
代表性论文（#共同作者，*通讯作者）：
1. Yingying Xu, Bin Zhang*, Jie Bao*. Production of γ-aminobutyric acid using corncob residue as carbohydrate feedstock by engineered Corynebacterium glutamicum. Biochemical Engineering Journal. 2025, 215: 109629.
2. Agustian Chen#, Bin Zhang#, Jie Bao*. Adaptive evolution of Paecilomyces variotiienhanced the biodetoxification of high-titer inhibitors in pretreated lignocellulosic feedstock. Bioresource Technology. 2024, 411, 131351.
3. Bin Zhang#, Ying Han#, Jie Bao*. Formulating the racemic lactic acids-free nitrogen ingredients from plant proteins for cellulosic chiral lactic acid fermentation. Industrial Crops & Products. 2024, 217, 118821.
4. Bin Zhang, Qingmei Han, Qi Liu, Ya Wang, Jie Bao*. Recycling of waste calcium carbonate in lignocellulosic biorefining chain for chiral lactic acid production. Bioresource Technology. 2024, 395, 130303.
5. Qi Liu#, Bin Zhang#, Mingshan Hu, Jie Bao*. Simultaneous enhancement of lignin-derived inhibitor tolerance and lipid accumulation of oleaginous yeast Trichosporon cutaneum by adaptive evolution. Process Biochemistry. 2024, 137, 20-29.
6. Tao Han#, Bin Zhang#, Hucheng Yang, Xiucai Liu, Jie Bao*. Changes in pH values allow for a visible detection of the endpoint in submerged liquid biodetoxification during biorefinery processing. ACS Sustainable Chemistry & Engineering. 2023, 11, 45, 16608-16617.
7. Bin Zhang#, Hucheng Yang#, Ya Wang#, Jie Bao*. Improving the dissolved oxygen level in high solids loading cellulosic sugar acids fermentation by restructuring the biorefinery chain. Biochemical Engineering Journal. 2023, 200, 109111.
8. Bin Zhang#, Dayu Ren#, Qi Liu#, Xiucai Liu, Jie Bao*. Coproduction of single cell proteins and lipid from lignocellulose derived carbohydrates and inorganic ammonia salt with soluble ammonia recycling. Bioresource Technology. 2023, 384:129345
9. Qi Liu, Yuanyuan Li, Weiliang Hou, Bin Zhang*, Jie Bao*. Cellulase mediated stress changes the cell wall structure of oleaginous yeast Trichosporon cutaneum during adaptive evolution with ultra-centrifugation fractionation. Biotechnology Journal. 2023, 2300091.
10. Shuai Shao#, Bin Zhang#, Ya Wang, Tao Han, Jie Bao*, Dry biorefinery conversion of cadmium-contaminated rice grain and straw to ethanol with complete collection and recycling of cadmium. Industrial Crops & Products. 2023, 197:116550.
11. Bin Zhang, Xiucai Liu, Jie Bao*, High solids loading pretreatment: the core of lignocellulose biorefinery as an industrial technology-An overview. Bioresource Technology. 2023, 369:128334.
12. Bin Zhang, Faryal A. Khushik, Baorui Zhan, Jie Bao*. Transformation of lignocellulose to starch-like carbohydrates by organic acid-catalyzed pretreatment and biological detoxification. Biotechnology & Bioengineering. 2021, 118: 4105-4118.
13. Bin Zhang, Jing Li, Xiucai Liu, Jie Bao*, Continuous simultaneous saccharification and co-fermentation (SSCF) for cellulosic L-lactic acid production. Industrial Crops & Products. 2022, 187: 115527.
14. Bin Zhang, Baorui Zhan, Jie Bao*. Reframing biorefinery processing chain of corn fiber for cellulosic ethanol production. Industrial Crops & Products. 2021, 170: 113791.
15. Bin Zhang, Lei Wu, Ya Wang, Jing Li, Baorui Zhan, Jie Bao*. Re-examination of dilute acid hydrolysis of lignocellulose for production of cellulosic ethanol after de-bottlenecking the inhibitor barrier. Journal of Biotechnology. 2022, 353: 36-43.
16. Tao Han#, Bin Zhang#, Hongxing Li, Hongsen Zhang, et al., Jie Bao*. Year-round storage operation of three major agricultural crop residue biomasses by performing dry acid pretreatment at regional collection depots. ACS Sustainable Chemistry & Engineering. 2021, 9: 4722-4734.
17. Wei Zeng#, Bin Zhang#, Mengxuan Li, Su Ding, Guiguang Chen, Zhiqun Liang*. Development and benefit evaluation of fermentation strategies for poly (malic acid) production from malt syrup by Aureobasidium melanogenum GXZ-6. Bioresource Technology. 2019, 274:479-487.
参与教学
本科生课程《生物工程过程设计》
研究生课程《Biomass Process Engineering》
生物能源与生物炼制实验室诚挚欢迎对木质纤维素生物炼制和工业微生物代谢工程改造有兴趣的本科生、研究生加入。导师组认真负责、科研氛围浓厚，期待您的加入！
联系方式：
上海市徐汇区梅陇路130号华东理工大学
邮编：200237
办公室：实验十八楼1303
微信：zhang136091127
电话：021-64251799
邮箱：binzh@ecust.edu.cn