杜磊
发布时间:2024-02-26   访问次数:6740


杜磊



食品科学与工程专业:硕士生导师

生物化工专业:硕士生导师

生物与医药专业(生物工程领域):硕士生导师



  杜磊,副教授,华东理工大学生物工程学院硕士生导师。2016年毕业于东京海洋大学,获应用生命科学专业博士学位。同年入职深圳大学材料学院从事博士后研究工作,合作导师Florian J. Stadler2019年入职华东理工大学生物工程学院食品科学与工程系。先后主持国家自然科学基金青年基金、上海市自然科学基金面上项目、微生物技术国家重点实验室(山东大学)开放课题和多项企业横向课题等科研项目。在Food HydrocollCarbohyr PolymMol Nutri Food ResProcess BiochemJ Rheology等杂志发表相关研究论文35篇。Polymers杂志客座编辑,Food and Health青年编委。


研究方向:

1. 食品亲水胶体

基于多糖、蛋白等食品亲水胶体的物性表征,研究其在功能性食品、益生菌及功能生物材料等领域的应用。

2. 生物活性肽

基于深度学习的生物活性肽高通量筛选和生物制造,开发功能生物活性肽产品。

3. 益生菌

功能益生菌发掘、高密度发酵及冻干保护剂开发。


主持或参加的国家基金项目:

(1) 国家自然科学基金青年基金项目(31801489),主持。

(2) 上海市自然科学基金面上项目(21ZR1416200),主持。

(3) 广东省水产品加工与安全重点实验室开放基金课题(GDPKLAPPS2001),主持。

(4) 微生物技术国家重点实验室(山东大学)开放课题(62450004042010),主持。

(5) 国家自然科学基金面上项目(21574086),项目骨干。


教学:

主讲本科生必修课程《食品工艺学实验》、《专业外语》和《毕业实习》。

 

代表性论文(*通讯作者)

1. Yuan Zou, Kum-Song. Ro, Chentian Jiang, Deyi Yin, Li Zhao, Daihui Zhang, Lei Du*, Jingli Xie. The anti-hyperuricemic and gut microbiota regulatory effects of a novel purine assimilatory strain, Lactiplantibacillus plantarum X7022, European Journal of Nutrition. 2023, DOI: 10.1007/s00394-023-03291-w.

2. Deyi Yin, Li Zhao, Sijing Deng, Yaqi Xie, Kum-Song Ro, Zeyong Yang, Lei Du*, JingLi Xie*, DongZhi Wei. Lactiplantibacillus plantarum X7022 plays roles on aging mice with memory impairment induced by D-galactose through restoring neuronal damage, relieving inflammation and oxidative stress, Probiotics and Antimicrobial Proteins. 2024, https://doi.org/10.1007/s12602-023-10208-w.

3. Kum-Song Ro, Li Zhao, Yangting Hu, Minli Ge, Lei Du*, Jingli Xie*. Anti-hyperuricemic properties and mechanism of Lactiplantibacillus plantarum X7023. Process Biochemistry. 2024, 136:26-37.

4. Dewei Xie, Yaling Shen, Eezeng Su, Lei Du*, Jingli Xie*, Dongzhi Wei. Anti-hyperuricemic, nephroprotective, and gut microbiota regulative effects of separated hydrolysate of alpha-Lactalbumin on potassium oxonate- and hypoxanthine-induced hyperuricemic mice. Molecular Nutrition & Food Research. 2023, 67(1), 2200162.

5. Lisong Hu, Yitong Xie, Shishuai Gao, Xiaoyu Shi, Chenhuan Lai, Daihui Zhang*, Chuanwei Lu, Yi Liu, Lei Du*, Xuezhi Fang*, Fen. Xu, Chunpeng Wang, Fuxiang Chu. Strain-induced orientation facilitates the fabrication of highly stretchable and tough xylan-based hydrogel for strain sensors. Carbohydrate Polymers. 2023, 312, 120827.

6. Chentian Jiang, Yafan Liu, Yijia Wang, Erzheng Su, Lei Du*, Ya-Jie Tang, Jingli Xie*, Dongzhi Wei. Hypolipidemic effects of the fermented soymilk with a novel Lactiplantibacillus plantarum strain X7021 on mice via modulating lipid metabolism and gut microbiota. International Journal of Food Science and Technology. 2022, 57(7): 4555-4565.

7. Lei Du, Kum-Song Ro, Yiji Zhang, Ya-Jie Tang, Wanbang Li, Jingli Xie*, Dongzhi Wei*. Effects of Lactiplantibacillus plantarum X7021 on physicochemical properties, purines, isoflavones and volatile compounds of fermented soymilk. Process Biochemistry. 2022, 113: 150-157.

8. Dewei Xie, Yunsheng Gao,Lei Du*, Yaling Shen, Jingli Xie, Dongzhi Wei. Effect of flavorzyme-modified soy protein on the functional properties, texture and microstructure of Mozzarella cheese analogue. Journal of Food Processing and Preservation. 2021, 45(11): e15963.

9. Lei Du, Chandra Sekhar Biswas, Yuhang Wu, Amin Ghavaminejad, Florian J. Stadler. Small and large amplitude oscillatory shear behavior of supramolecular gels based on dopamine-boronic acid interactions.Journal of Rheology. 2019, 63 (3), 391-404.

10. Lei Du, Amin Ghavaminejad, Zhi-chao Yan, Chandra Sekhar Biswas, Florian J. Stadler. Effect of a functional polymer on the rheology and microstructure of sodium alginate. Carbohydrate Polymers, 2018, 199: 58-67.

11. Lei Du, Amin Ghavaminejad, Mohammad Vatankhah-varnoosfaderani, Florian. J. Stadler. Study of the interactions of zwitterions and carbon nanotubes by nonlinear rheology in aqueous environment. Langmuir,2019, 35:1964-1972.

12. Lei Du, Tom Brenner, Jingli Xie, Shingo Matsukawa. A study on phase separation behavior in kappa/iota carrageenan mixtures by micro DSC, rheological measurements and simulating water and cations migration between phases. Food Hydrocolloids, 2016, 55: 81-88.

 

发明专利:

[1] 谢静莉,方明,李鹏,吴艳玲,杜磊,魏东芝. 降血压多肽,ZL 2013101240332.

 

联系方式:

办公室:实验18707

电话:021-64251803

通讯地址:上海市徐汇区梅陇路130号华东理工大学,200237

邮箱:dulei@ecust.edu.cn