徐慧颖
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徐慧颖


生物化学与分子生物学专业:硕士生导师

 

徐慧颖,女,1988年出生于河南商丘,博士,华东理工大学生物工程学院硕士生导师。20166月毕业于复旦大学化学系,获理学博士学位。随后进入华东理工大学生物工程学院从事师资博士后研究工作,合作导师叶邦策教授。201811月留校任教,先后主持国家、省部级项目2项,包括国家自然科学基金青年基金项目、中国博士后科学基金二等资助项目,同时还主持中央高校基本科研业务费探索基金一项。在Analytical ChemistryBiosensors and BioelectronicsChemical Communications等本领域重点期刊上发表SCI收录论文10余篇,其中第一作者8篇。

 

教育经历

20119-20166复旦大学,化学系,博士

20069-20106河南师范大学,生命科学学院,学士

 

研究方向:

1. 纳米生物分析技术及微流控生物传感系统的开发。针对一些疾病标志物的经典分析方法灵敏度低、操作步骤冗杂等问题,利用微流控技术的优势以及功能纳米材料和功能核酸的优良特性,构建可用于生理活性物质分析的传感技术。

2. 外泌体调控机理研究及其功能化应用。借助微流控芯片体系的构建,研究外泌体介导细胞间相互作用的机理。并利用外泌体免疫原性低、运输效率高、稳定性好等优势,对其进行功能化修饰,用于药物递送及疾病治疗。

 

 

代表性论文:

1. Yu Zhou, Huiying Xu*, Hua Wang and Bang-Ce Ye *. Detection of breast cancer-derived exosomes using the horseradish peroxidase-mimicking DNAzyme as an aptasensor. Analyst, 2020, 145, 107.

2. Huiying Xu, Bang-Ce Ye*. Advances in biosensing technologies for analysis of cancer-derived exosomes. Trends in Analytical Chemistry,2020, 123, 115773.

3. Huiying Xu+, Chong Liao+, Peng Zuo, Ziwen Liu, and Bang-Ce Ye*. A magnetic-based microfluidic device for on-chip isolation and detection of tumor-derived exosomes. Analytical Chemistry, 2018, 90, 13451.

4. Huiying Xu, Chong Liao, Yujie Liu, Bang-Ce Ye* and Baohong Liu*. Iron phthalocyanine decorated nitrogen-doped graphene biosensing platform for real-time detection of nitric oxide released from living cells. Analytical Chemistry, 2018, 90, 4438.

5. Huiying Xu, Fenghua Geng, Xiangyu Jiang, Congying Shao, Yongxiang Wang*, Kefeng Wang, Peng Qu, Maotian Xu, Bang-Ce Ye*. Design of metal-ion-triggered assembly of label-free split G-quadruplex/duplex DNA for turn-on detection of Hg2+ in fetal calf serum. Sensors and Actuators B: Chemical, 2018, 255, 1024.

6. Huiying Xu, Jingjing Xiao, Baohong Liu*, Sophie Griveau, Fethi Bedioui, Enhanced electrochemical sensing of thiols based on cobalt phthalocyanine immobilized on nitrogen-doped graphene. Biosensors and Bioelectronics, 2014, 66, 438.

7. Huiying Xu, Fenghua Geng, Yongxiang Wang,* Maotian Xu, Xinhe Lai, Peng Qu, Yintang Zhang, and Baohong Liu*. A label-free fluorescent molecular switch for a DNA hybridization assay utilizing a G-quadruplex selective auramine. Chemical Communications, 2015, 51, 8622.

8. Huiying Xu, Jingjing Xiao, Ling Yan, Lina Zhu, Baohong Liu*. An electrochemical sensor for selective detection of dopamine based on nickel tetrasulfonated phthalocyanine functionalized nitrogen-doped graphene nanocomposites. Journal of Electroanalytical Chemistry, 2016, 779, 92.

 

联系方式:

电话:021-64253832, 13817258018

邮箱:xuhuiying@ecust.edu.cn

地址:上海市徐汇区梅陇路130华东理工大学实验十八楼713