鲍杰
发布人:生工学院网站管理员  发布时间:2016-10-19   动态浏览次数:971

鲍杰

生物工程专业:博士生导师/硕士生导师 
    生物化工专业:博士生导师/硕士生导师 
    生物工程领域:工程硕士生导师

工学博士,教授、博士生导师,生物炼制与能源生物技术团队学术带头人。研究方向为生物炼制与生物能源,研究领域聚焦于木质纤维素生物炼制和生物能源方向的应用基础研究和工业应用。

实验室网页:http://sklbe.ecust.edu.cn/biomasslab


学历

1997-2001  工学博士,日本国立山口大学生物反应工学专业

1995-1997  工学硕士,浙江大学化学反应工程专业

1980-1984  工学学士,南京理工大学化学工程专业


工作经历

2006-现在华东理工大学生物工程学院教授、博士生导师

2002-2006  美国加州大学戴维斯分校化学工程系博士后研究员

2001-2002  日本国立冈山大学工学部客座研究员

1984-1995  中石化齐鲁石化研究院工程师、课题组长


学术兼职

1.副主编 (Associate Editor), Applied Biochemistry and Biotechnology (Springer),2012年至今;

2.编委 (Editorial Board Member), Biofuels, Bioproducts and Biorefining (Wiley),2008年至今;

3.编委 (Editorial Board Member), Bioprocess and Biosystems Engineering (Springer),2012年至今。

4.编委, 华东理工大学学报(自然科学版),2009年至今。

研究方向

1.生物炼制过程技术:从木质纤维素生物质生产燃料乙醇、生物柴油(油脂)、有机酸、氨基酸、多元醇等生物燃料和生物基化学品的工业生物技术研究。提出了以干式稀酸预处理、生物脱毒、高固体含量糖化与发酵为代表的干法生物炼制技术,在实现零废水、低能耗、低成本的前提下,达到了迄今最高的生物转化技术指标。建立了以CFD和Aspen plus流程模拟为核心的成套生物炼制技术。正在进行的生物炼制产业化示范正在逐步实现木质纤维素原料对粮食和石油原料的替代。

2.生物炼制代谢工程:针对抑制物脱毒、戊糖代谢等生物炼制发酵区别于常规粮食淀粉发酵的特征关键问题,发现了一系列重要的生物脱毒微生物,建立了独特的木质纤维素原料生物脱毒技术,以及基于组学分析的生物脱毒机制和代谢工程改造;对生物炼制发酵微生物进行了代谢工程和适应性进化改造,构建了一系列适合于生物炼制体系的超级抗逆工程菌。

主讲课程

1.本科生专业课:生物炼制工程(Biorefinery Engineering)

2.本科生专业课:过程工程过程设计(Aspen plus在生物工程设计上的应用)

3.研究生全英文专业课(硕士):生物能源过程工程(Bioenergy Process Engineering)

4.研究生专业课(博士):生物化工进展


研究团队

2016年度研究团队包括教师3人,博士生12人(包括国际学生2人),硕士生12人。

科研课题

2006年实验室成立至今,作为课题负责人主持国家级、省部级等研究课题30多项。代表性课题包括木质纤维素降解转化过程强化的工程学原理与方法(973)、极限低水稀酸预处理技术体系研究(863)、农作物秸秆制备生物化工醇产业化示范(863)、复杂酶反应体系的抑制效应解析与关键路径的加速(国家自然科学基金)、节能与清洁型木质纤维素生产燃料乙醇过程的关键技术研究(中石油)等。


近期学术著作

1.Bioreactor Engineering Research and Industrial Applications II, Advances in Biochemical Engineering/Biotechnology, Volume 152, 2016. Editors: Jie Bao, Qin Ye, Jian-Jiang Zhong. ISBN: 978-3-662-48346-6 (Print), 978-3-662-48347-3 (eBook). Springer, Berlin, Heidelberg, Germany, 2016.

2.Bioreactor Engineering Research and Industrial Applications I, Advances in Biochemical Engineering /Biotechnology, Volume 155, 2016. Editor: Editors: Qin Ye, Jie Bao, Jian-Jiang Zhong. ISBN: 978-3-662-49159-1 (Print), 978-3-662-49161-4 (eBook)

3.生物炼制产品与技术,鲍杰,高秋强,张建,曹学君,邓红波译。上海科学技术出版社,2013. ISBN 978-7-5478-1568-7

4.现代生物能源技术-美国国家可再生能源实验室生物能源技术报告(应用生物技术大系丛书),鲍杰译,科学出版社,2009. ISBN 978-7-03-024519-9


近期代表性国际期刊论文

1.Xia Wang, Qiuqiang Gao, Jie Bao*. Enhancement of furan aldehydes conversion in Zymomonas mobilis by elevating dehydrogenase activity and cofactor regeneration. Biotechnology for Biofuels 2017, 10:24.

2.Ping-Ping Zhou, Jiao Meng, Jie Bao*. Fermentative production of high titer citric acid from corn stover feedstock after dry dilute acid pretreatment and biodetoxification. Bioresource Technology, 2017, 224:563-572.

3.Hongsen Zhang1, Xushen Han1, Chengxiang Wei1, Jie Bao*.Oxidative production of xylonic acid using xylose in distillation stillage of cellulosic ethanol fermentation broth by Gluconobacter oxydans. Bioresource Technology, 2017, 224:573-580.

4.Hongsen Zhang1, Gang Liu1, Jian Zhang, Jie Bao*. Fermentative production of high titer gluconic and xylonic acids from corn stover feedstock by Gluconobacter oxydans and techno-economic analysis. Bioresource Technology, 2016, 219:123-131.

5.Juan Wang, Qiuqiang Gao, Huizhan Zhang, Jie Bao*. Inhibitor degradation and lipid accumulation potentials of oleaginous yeast Trichosporon cutaneum using lignocellulose feedstock. Bioresource Technology, 2016, 218:892-901.

6.Juan Wang, Qiuqiang Gao*, Jie Bao*. Genome sequence of Trichosporon cutaneum ACCC 20271: An oleaginous yeast with excellent lignocellulose derived inhibitor tolerance. Journal of Biotechnology, 2016, 228:50-51.

7.Yanqing He, Jian Zhang, Jie Bao*. Acceleration of biodetoxification on dilute acid pretreated lignocellulose feedstock by aeration and the consequent ethanol fermentation evaluation. Biotechnology for Biofuels, 2016, 9:19.

8.Hongsen Zhang, Jian Zhang, Jie Bao*. High titer gluconic acid fermentation by Aspergillus niger from dry dilute acid pretreated corn stover without detoxification. Bioresource Technology, 2016, 203:211-219.

9.Jian Zhang1, Shuai Shao1, Jie Bao*. Long term storage of dilute acid pretreated corn stover feedstock and ethanol fermentability evaluation. Bioresource Technology, 2016, 201:355-359.

10.Xia Yi1, Peng Zhang1, Jiaoe Sun, Yi Tu, Qiuqiang Gao, Jian Zhang, Jie Bao*. Engineering wild-type robust Pediococcus acidilactici strain for high titer L- and D-lactic acid production from corn stover feedstock. Journal of Biotechnology,2016, 217:112-121.

11.Weiliang Hou1, Ruixin An1, Jian Zhang, Jie Bao*. On-site measurement and modeling of rheological property of corn stover hydrolysate at high solids content. Biochemical Engineering Journal, 2016, 107: 61-65.

12.Weiliang Hou, Jian Zhang, Jie Bao*. Rheology evolution and CFD modeling of lignocellulose biomass during extremely high solids content pretreatment. Biochemical Engineering Journal, 2016, 105:412-419.

13.Gang Liu, Jian Zhang, Jie Bao*. Cost evaluation of cellulase enzyme for industrial scale cellulosic ethanol production based on rigorous Aspen plus modeling. Bioprocess and Biosystems Engineering, 2016, 39:133-140.

14.Jian Zhang, Weiliang Hou, Jie Bao*. Reactors for high solid loading pretreatment of pretreatment of lignocellulosic biomass. Advances in Biochemical Engineering/Biotechnology, 2016, 152:75-90.

15.Hanqi Gu, Jian Zhang, Jie Bao*. High tolerance and physiological mechanism of Zymomonas mobilis to phenolic inhibitors in ethanol fermentation of corncob residue. Biotechnology and Bioengineering, 2015, 112:1770-1782.

16.Xia Yi, Hanqi Gu, Qiuqiang Gao, Z. Lewis Liu*, Jie Bao*.Transcriptome analysis of Zymomonas mobilis ZM4 reveals mechanisms of tolerance and detoxification of phenolic aldehyde inhibitors from lignocellulose pretreatment. Biotechnology for Biofuels, 2015, 8:153.

17.Xia Wang, Qiuqiang Gao, Jie Bao*. Transcriptional analysis of Amorphotheca resinae ZN1 on biological degradation of furfural and 5-hydroxymethylfurfural derived from lignocellulose pretreatment. Biotechnology for Biofuels, 2015, 8:136.

18.Gang Liu1, Jiaoe Sun1, Jian Zhang1,Yi Tu,Jie Bao*. High titerL-lactic acid production from corn stoverwith minimum wastewater generationand techno-economic evaluation based on Aspen plus modeling. Bioresource Technology, 2015, 198:803-810.

19.Ke Liu, Jian Zhang, Jie Bao*. Two stage hydrolysis of corn stover at high solids content for mixing power saving and scale-up applications. Bioresource Technology, 2015, 196:716-720.

20.Abdul Sattar Qureshi, Jian Zhang, Jie Bao*. High ethanol fermentation performance of the dry dilute acid pretreated corn stover by an evolutionarily adapted Saccharomyces cerevisiae strain. Bioresource Technology, 2015, 189:399-404.

21.Jia-Qing Zhu, Lei Qin, Wen-Chao Li, Jian Zhang, Jie Bao, Yao-Dong Huang, Bing-Zhi Li, Ying-Jin Yuan. Simultaneous saccharification and co-fermentation of dry diluted acid pretreated corn stover at high dry matter loading: Overcoming the inhibitors by non-tolerant yeast. Bioresource Technology, 2015, 198:39-46.

22.Juan Wang, Huizhan Zhang*, Jie Bao*. Characterization of inulin hydrolyzing enzyme(s) in oleaginous yeast Trichosporon cutaneum in consolidated bioprocessing of microbial lipid fermentation. Applied Biochemistry and Biotechnology, 2015, 177:1083-1098.

23.Qureshi Abdul Sattar, Jian Zhang*, Jie Bao*. Cellulosic ethanol fermentation using Saccharomyces cerevisiae seeds cultured by pretreated corn stover material. Applied Biochemistry and Biotechnology, 2015, 175:3173-3183.

24.Hanjie Li, Chenlin Ye, Ke Liu, Hanqi Gu, Weitao Du, Jie Bao*. Analysis of particle size reduction on overall surface area and enzymatic hydrolysis yield of corn stover. Bioprocess and Biosystems Engineering 2015, 38:149-154.

25.Zichen Luo, Jie Bao*. Secretive expression of heterologous β-glucosidase in Zymomonas mobilis. Bioresources and Bioprocessing, 2015, 2:29.

26.Long-Ping Zhang, Jian Zhang, Chuan-Hang Li, Jie Bao*. Rheological characterization and CFD modeling of corn stover-water mixing system at high solids loading for dilute acid pretreatment. Biochemical Engineering Journal 2014, 90:324-332.

27.Yanqing He, Zhenhong Fang, Jian Zhang, Xinliang Li, Jie Bao*. De-ashing treatment of corn stover improves the efficiencies of enzymatic hydrolysis and consequent ethanol fermentation. Bioresource Technology 2014, 169:552-558.

28.Cheng Lei, Jian Zhang, Lin Xiao, Jie Bao*. An alternative feedstock of corn meal for industrial fuel ethanol production: Delignified corncob residue. Bioresource Technology 2014, 167:555-559.

29.Zhen-Hong Fang, Jian Zhang, Qi-Ming Lu, Jie Bao*. Process development of short-chain polyols synthesis from corn stover by combination of enzymatic hydrolysis and catalytic hydrogenolysis. Biotechnology Reports 2014, 3:15-20.

30.Zichen Luo, Qiuqiang Gao, Xinliang Li, Jie Bao*. Cloning of LicB from Clostridium thermocellum and its efficient secretive expression of thermostable β-1,3-1,4-glucanase. Applied Biochemistry and Biotechnology, 2014, 173:562-570.

31.Yanqing He, Jian Zhang, Jie Bao*. Dry dilute acid pretreatment by co-currently feeding of corn stover feedstock and dilute acid solution without impregnation. Bioresource Technology 2014, 158:360-364.

32.Hong Ran, Jian Zhang, Qiuqiang Gao, Zhanglin Lin, Jie Bao*. Analysis of biodegradation performance of furfural and 5-hydroxymethylfurfural by Amorphotheca resinae ZN1. Biotechnology for Biofuels 2014, 7:51.

33.Yanqing He, Longping Zhang, Jian Zhang*, Jie Bao*. Helically agitated mixing in dry dilute acid pretreatment enhances the bioconversion of corn stover into ethanol. Biotechnology for Biofuels 2014, 7:1.

34.Hanqi Gu, Jian Zhang, Jie Bao*. Inhibitor analysis and adaptive evolution of Saccharomyces cerevisiae for simultaneous saccharification and ethanol fermentation from industrial waste corncob residues. Bioresource Technology, 2014, 157:6-13.

35.Qiuqiang Gao, Zhenyang Cui, Jian Zhang, Jie Bao*. Lipid fermentation of corncob residues hydrolysate by oleaginous yeast Trichosporon cutaneum. Bioresource Technology 2014, 152:552-556.

36.Lihao Guo, Jian Zhang, Fengxian Hu, Dewey DY Ryu, Jie Bao*. Consolidated bioprocessing of highly concentrated Jerusalem artichoke tubers for simultaneous saccharification and ethanol fermentation. Biotechnology and Bioengineering 2013, 110:2606-2615.

37.Hongwei Dong, Liqiang Fan, Zichen Lu, Jianjiang Zhong, Dewey D. Y. Ryu, Jie Bao*. Improvement of ethanol productivity and energy efficiency by degradation of inhibitors using recombinant Zymomonas mobilis (pHW20a-fdh). Biotechnology and Bioengineering 2013, 110:2395-2404.

38.Thai Ha Dao, Jian Zhang, Jie Bao*. Characterization of inulin hydrolyzing enzyme(s) in commercial glucoamylases and its application in lactic acid production from Jerusalem artichoke tubers (Jat). Bioresource Technology 2013, 148:157-162.

39.Jian Zhang, Zhenhong Fang, Hongbo Deng, Xiaoxi Zhang, Jie Bao*. Cost analysis of cassava cellulose utilization scenarios for ethanol production on flowsheet simulation platform. Bioresource Technology 2013, 134:298-306.

40.Kai Zhao, Qingan Qiao, Deqiang Chu, Hanqi Gu, Thai Ha Dao, Jian Zhang, Jie Bao*. Simultaneous saccharification and high titer lactic acid fermentation of corn stover using a newly isolated lactic acid bacterium Pediococcus acidilactici DQ2. Bioresource Technology 2013, 135:481-489.

41.Kehong An, Fengxian Hu, Jie Bao*. Simultaneous saccharification of inulin and starch using commercial glucoamylase and the subsequent bioconversion to high titer sorbitol and gluconic acid. Applied Biochemistry and Biotechnology 2013, 171:2093-2104.

42.Wei Liu, Yumei Wang, Zhanchun Yu, Jie Bao*. Simultaneous saccharification and microbial lipid fermentation of corn stover by oleaginous yeast Trichosporon cutaneum. Bioresource Technology2012, 118:13-14.

43.Jian Zhang, Jie Bao*. A modified method for calculating practical ethanol yield at high lignocellulosic solids content and high ethanol titer. Bioresource Technology 2012, 116:74-79.

44.Deqiang Chu, Jian Zhang, Jie Bao*. Simultaneous saccharification and ethanol fermentation of corn stover at high temperature and high solids loading by a thermotolerant strain Saccharomyces cerevisiae DQ1. Bioenergy Research 2012, 5:1020-1026.

45.Deqiang Chu, Hongbo Deng, Xiaoxi Zhang, Jian Zhang, Jie Bao*. A simplified filter Paper assay method of cellulase enzymes based on HPLC analysis. Applied Biochemistry and Biotechnology 2012, 167:190-196.

46.Jianming Liu, Xiujuan Xin, Chunxiu Li, Jianhe Xu, Jie Bao*.Cloning of thermostable cellulase genes of Clostridium thermocellum and their secretive expression in Bacillus subtilis. Applied Biochemistry and Biotechnology  2012, 166:652-662.

47.Jian Zhang, Xin Ren, Wenqun Chen, Jie Bao*. Biological pretreatment of corn stover by solid state fermentation of Phanerochaete chrysosporium. Frontier of Chemical Science and Engineering 2012, 6:146-151.

48.Yumei Wang, Wei Liu, Jie Bao*. Repeated batch fermentation with water recycling and cell separation for microbial lipid production. Frontier of Chemical Science and Engineering 2012, 6(4):453-460.

49.Xiao Huang, Yumei Wang, Wei Liu, Jie Bao*.. Biological removal of inhibitors leads to the improved lipid production in the lipid fermentation of corn stover hydrolysate by Trichosporon cutaneum. Bioresource Technology2011, 102:9705-9709.

50.Jian Zhang, Xiusheng Wang, Deqiang Chu, Yanqing He, Jie Bao*. Dry pretreatment of lignocellulose with extremely low steam and water usage for bioethanol production. Bioresource Technology 2011, 102:4480-4488.

51.Hongwei Dong, Jie Bao*, Dewey D. Y. Ryu*, Jianjiang Zhong*. Design and construction of improved new vectors for Zymomonas mobilis recombinants. Biotechnology and Bioengineering 2011, 108:1616-1627.

52.Dexi Bi, Deqiang Chu, Pei Zhu, Chenyang Lu, Chao Fan, Jian Zhang, Jie Bao*. Utilization of dry distiller’s grain and soluble as  trient supplement in the simultaneous saccharification and ethanol fermentation at high solids loading of corn stover. Biotechnology Letter 2011, 33:273-276.

53.Xiusheng Wang, Andong Song, Jie Bao*. Effect of calcium carbonate in waste office paper on enzymatic hydrolysi efficiency and the enhancement procedures. Korea Journal of Chemical Engineering 2011, 28:550-556.

54.Hongwei Dong, Jie Bao*. Biofuel via biodetoxification (News and Views). Nature Chemical Biology 2010, 6:316-318.

55.Jian Zhang, Deqiang Chu, Juan Huang, Zhanchun Yu, Gance Dai, Jie Bao*. Simultaneous saccharification and ethanol fermentation at high corn stover solids loading in a helical stirring bioreactor. Biotechnology and Bioengineering 2010, 105:718-728.

56.Jian Zhang, Zhinan Zhu, Xiaofeng Wang, Nan Wang, Wei Wang, Jie Bao*. Biodetoxification of toxins generated from lignocellulose pretreatment using a newly isolated fungus Amorphotheca resinae ZN1 and the consequent ethanol fermentation. Biotechnology for Biofuels2010, 3:26.

57.Changjun Liu, Hongwei Dong, Jianjiang Zhong, Dewey DY Ryu, Jie Bao*. Sorbitol production using recombinant Zymomonas mobilis strain. Journal of Biotechnology 2010, 148:105-112.

58.Zhinan Zhu, Jiping Shi, Zhihua Zhou, Fengxian Hu, Jie Bao*. Photo-fermentation of Rhodobacter sphaeroides for hydrogen production using lignocellulose-derived organic acids. Process Biochemistry 2010, 45:1894-1898.