马昱澍
生物化学与分子生物学专业:硕士生导师
微生物学专业:硕士生导师
生物工程领域 :工程硕士生导师
男,1973年6月出生,博士,华东理工大学生物工程学院副教授,硕士生导师
学历及工作经历
1991年10月-1997年6月
俄罗斯联邦国立莫斯科大学生物系生物化学专业,获得生物化学硕士学位
1997年7月-2000年6月
俄罗斯联邦国立莫斯科大学生物系生物化学专业,获得生物化学博士学位
2000年9月-2002年9月
复旦大学遗传工程国家重点实验室博士后
2002年10月至今
华东理工大学生物工程学院副教授
近期发表论文
1. Identification of an interaction between EI and a histidine kinase-response regulator hybrid protein in Gluconobacter oxydans. Li S, Ma Y, Wei D. Biochem Biophys Res Commun. 2016 Feb 5;470(2):331-5. doi: 10.1016/j.bbrc.2016.01.052. Epub 2016 Jan 11.
2. Construction of an Oscillator Gene Circuit by Negative and Positive Feedbacks. Shen S, Ma Y, Ren Y, Wei D. J Microbiol Biotechnol. 2016 Jan 28;26(1):139-44. doi: 10.4014/jmb.1507.07019.
3. Phosphorylation of HPr by HPr kinase in Gluconobacter oxydans 621H. Zhang P, Ma Y, Wang F, Wei D. Protein Pept Lett. 2014 Jun;21(6):597-601.
4. Construction of a novel shuttle vector for use in Gluconobacter oxydans. Zhang L, Lin J, Ma Y, Wei D, Sun M. Mol Biotechnol. 2010 Nov;46(3):227-33. doi: 10.1007/s12033-010-9293-2.
5. Characterization of a novel NADPH-dependent oxidoreductase from Gluconobacter oxydans. Chen M, Lin J, Ma Y, Wei D. Mol Biotechnol. 2010 Oct;46(2):176-81. doi: 10.1007/s12033-010-9283-4.
6. Development of recombinant Escherichia coli whole-cell biocatalyst expressing a novel alkaline lipase-coding gene from Proteus sp. for biodiesel production. Gao B, Su E, Lin J, Jiang Z, Ma Y, Wei D. J Biotechnol. 2009 Jan 15;139(2):169-75. doi: 10.1016/j.jbiotec.2008.10.004. Epub 2008 Oct 22.
7. Efficient display of active lipase LipB52 with a Pichia pastoris cell surface display system and comparison with the LipB52 displayed on Saccharomyces cerevisiae cell surface. Jiang Z, Gao B, Ren R, Tao X, Ma Y, Wei D. BMC Biotechnol. 2008 Jan 28;8:4. doi: 10.1186/1472-6750-8-4.
8. Expression of two old yellow enzyme homologues from Gluconobacter oxydans and identification of their citral hydrogenation abilities. Yin B, Yang X, Wei G, Ma Y, Wei D. Mol Biotechnol. 2008 Mar;38(3):241-5. Epub 2007 Dec 5.
9. Screening of a phage display library of exendin-4 mutants with the extracellular domain of rat GLP-1 receptor. Yin X, Ma Y, Liu M, Gao W, Wei D. Protein Pept Lett. 2007;14(8):816-21.
10. Display of adenoregulin with a novel Pichia pastoris cell surface display system. Ren R, Jiang Z, Liu M, Tao X, Ma Y, Wei D. Mol Biotechnol. 2007 Feb;35(2):103-8.
11. The transduction of His-TAT-p53 fusion protein into the human osteogenic sarcoma cell line (Saos-2) and its influence on cell cycle arrest and apoptosis. Jiang L, Ma Y, Wang J, Tao X, Wei D. Mol Biol Rep. 2008 Mar;35(1):1-8. Epub 2007 Jan 6.
12. Expression and purification of exendin-4 dimer in Escherichia coli and its interaction with GLP-1 receptor in vitro. Yi L, Yin X, Wei D, Ma Y. Protein Pept Lett. 2006;13(8):823-7.
13. A novel psychrophilic lipase from Pseudomonas fluorescens with unique property in chiral resolution and biodiesel production via transesterification. Luo Y, Zheng Y, Jiang Z, Ma Y, Wei D. Appl Microbiol Biotechnol. 2006 Nov;73(2):349-55. Epub 2006 May 25.
14. Enhancing enzymatic activity of penicillin G acylase by coexpressing pcm gene.
15. Wang T, Zhu H, Ma X, Fei Z, Ma Y, Wei D. Appl Microbiol Biotechnol. 2006 Oct;72(5):953-8. Epub 2006 Mar 21.
16. Structure-based stabilization of an enzyme: the case of penicillin acylase from Alcaligenes faecalis. Wang T, Zhu H, Ma X, Ma Y, Wei D. Protein Pept Lett. 2006;13(2):177-83.
17. Cloning and expression of a novel lipase gene from Pseudomonas fluorescens B52.
18. Jiang Z, Zheng Y, Luo Y, Wang G, Wang H, Ma Y, Wei D. Mol Biotechnol. 2005 Oct;31(2):95-101.
19. Characterization of two novel lipase genes isolated directly from environmental sample. Jiang Z, Wang H, Ma Y, Wei D. Appl Microbiol Biotechnol. 2006 Apr;70(3):327-32. Epub 2005 Jul 8.
20. Expression and purification of exendin-4, a GLP-1 receptor agonist, in Escherichia coli. Yin X, Wei D, Yi L, Tao X, Ma Y. Protein Expr Purif. 2005 Jun;41(2):259-65.
研究方向
1.微生物碳氮代谢调控
2.合成生物学基础理论
联系方式
地址:华东理工大学鲁华所401室
电话:021-64253287
Email:myushu@ecust.edu.cn