黄青春  博士, 教授    

Tel:  021-64253724;   E-mail:  qchuang@ecust.edu.cn

  个人简介 
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  黄青春，1969年生。博士，教授。上海市昆虫学会会员，Chin J Biol期刊编委。1993年获学士学位，1998年获硕士学位；2001年获博士学位。2001年9月至今任华东理工大学讲师、副教授、教授。2011年6月-2012年6月美国Purdue大学访问学者。主要研究领域为农药的生物学与应用。研究生招生专业为(1)农药学和(2)生物化学与分子生物学。

在Chemosphere, Environ Toxic Pharmacol, J Agri Food Chem, Environ Toxic Chem, Pestic Biochem Physiol, J Insect Sci, Pest Manag Sci, Arch Phytopathol Plant Prot, J Asia-Pacific Entomol, Monatsh Chem, Carbohydrate Res, Chemistry and Biodiversity, J Environ Sci Health等国际同领域重要学术期刊发表SCI论文70余篇，申请并公开发明专利近20项。2004年获得教育部自然科学一等奖1项。作为课题负责人，先后完成了国家自然科学基金项目(30400295)、国家科技支撑计划项目(2006BAE01A03-9)、上海市科委重点和基础研究项目(034319245, 073919107, 15431906800)等课题；作为研究成员，参与了国家973项目(2003CB114402, 2010CB126101)、863项目(2001AA235011, 2005AA235050)等国家和省部级研究课题。

研究方向 
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方向一：农药生物学

开展生物农药和化学农药的高效筛选、作用机制、代谢与转化、及环境毒理研究。

方向二：细胞毒理学

针对生物农药和化学农药的新机制，开展细胞发育与凋亡、DNA损伤修复、信号转导和调控相关的毒理学研究。 

发表的部分研究论文
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[1]  Wu X, Zhang L, Yang C, Zong M,HuangQ*, et al. Detection on emamectin benzoate-induced apoptosis and DNA damage in Spodoptera frugiperda Sf9 cell line. Pestic Biochem  Physiol 2016, 126: 6-12. 

[2] Liu P, Shu C, Liu L, HuangQ, Peng Y. Design and synthesis of thiourea derivatives with sulfur-containing heterocyclic scaffolds as potential tyrosinase inhibitors. Bioorg Med Chem 2016, 24: 1866-1871.
[3] HuangQ*,  Wu X, Yu X, et al. Suppression of carbendazim-susceptible and -resistant Sclerotinia sclerotiorum with Macleya alkaloids. Arch Phytopathol Plant Prot 2015, 48(6): 485-494.

[4] Li D, HuangQ*,  Lu M, Zhang L, et al. The organophosphate insecticide chlorpyrifos confers its genotoxic effects by inducing DNA damage and cell apoptosis. Chemosphere 2015, 135: 387-393.
[5] Li D, Wu X, Yu X, HuangQ*, et al. Synergistic effect of nonionic surfactants Tween 80 and PEG6000 on cytotoxicity of insecticides. Environ Toxicol Pharmacol 2015, 39: 677–682.
[6] HuangQ*, Wu X, Yu X, Zhang L, et al. Comparison of the cytotoxic impact of chlorfluazuron on selected insect and human cell lines. Environ Toxicol Chem 2015, 34: 1675-1682.
[7] Xu W, HuangQ*, Wu X, Yu X, et al. Property of midgut a-amylase from Mythimna separata (Lepidoptera: Noctuidae) larvae and its responses to potential inhibitors in vitro. J Insect Sci 2014, 14(282). 

[8] Xiao C, HuangQ*. Inhibitory effects of two 1,3,4-oxadiazoles on larval growth and α-amylase in the midguts of Mythimna separata larvae. J Asia-Pacific Entomol 2014, 17: 251-256. 

[9] Guo P, Huang J, HuangQ, Qian X. Synthesis of novel 1,3-oxazole derivatives with insect growth-inhibiting activities. Chin Chem Let 2013, 24: 957-961. 

[10] Qian Q, Zhu Y, Zhang M, Lu D, Cao W, Song L, HuangQ*. Efficient synthesis and insecticidal activity of novel pyridin-3-yl-[1,2,4]triazolo [3,4-b][1,3,4]thiadiazoles. Monatshefte für Chemie 2013, 144: 231-236. 

[11] Wu M, Zhao W, Jin G, HuangQ, Cao S. Synthesis and insecticidal activities of novel analogues of flubendiamide containing a hexafluoroisopropanol moiety. Chin J Chem 2012, 30: 1310-1314. 

[12] Zhu Q, He Y, Yao J, Liu Y, Tao L, HuangQ*. Effects of sublethal concentrations of the chitin synthesis inhibitor, hexaflumuron, on the development and hemolymph physiology of the cutworm, Spodoptera litura. J Insect Sci 2012, 12 (27).

[13] HuangQ*, Y Liu, T Zhan, Y Deng, Y He. Comparable Susceptibility of Human 293 Cells and  Insect Tn-5B1-4 Cells to Photoactivated α-Terthienyl. J. Agric. Food Chem. 2010, 58(5): 2637-2642.

[14] Li B, H Yuan, J Fang, L Tao, Huang Q*, X Qian*, Z Fan. Recent progress of highly efficient in vivo  biological  screening for novel agrochemicals in China. Pest Manag. Sci. 2010, 66: 107-112.

[15] Huang Q*,  Deng Y,  Zhan T,  He Y. Differential synergism of fipronil by piperonyl butoxide in the susceptible and resistant Chilo suppressalis. Journal of Insect Science 2010, 10/162. 

[16] Deng Y, He Y, Zhan T, Huang Q*. Novel 2′-hydroxylfurylchalcones: Synthesis and biological activity. Carbohydrate Research 2010, 5: 1844-1855.

[17] Huang Q*, J. Wu, Y. Kong, et al. Surfactant effect on persistence of oxadiazolyl 3(2H)-pyridazinones against Pseudaletia separata Walker.  J. Environ. Sci. Health 2007, 42: 305-310.

[18] Cai M, Z Li, F Fan, Q Huang, X Shao, G Song. Design and synthesis of novel insecticides based on serotonergic ligand PAPP. J. Agric. Food Chem. 2010, 58, 2624-2629.

[19] Cao S, X Qian, X Tang, J Zhang, Q Huang, H Sun. Heptafluoroisopropyl-containing benzoyl phenyl ureas and their applications. PCT/CN2009/070858, WO/2009/115040.

[20] Huang Q*, Liu M, Feng J, et al.. Effect of Dietary benzoxadiazole on larval development, cuticle enzyme and antioxidant defense system in  housefly (Musca domestica). Pest. Biochem. Physiol. 2008, 90: 119-125. 

[21] Huang Q*, Qian X, Song G, et al. The toxic and antifeedant activity of 2H-pyridazin-3-one-substituted 1,3,4-oxadiazoles against the  armyworm Pseudaletia separata Walker and other insects and mites. Pest Manag. Sci. 2003, 59: 933-939.

[22] Huang Q*, Liu L, Xiao C, et al. Photolarvicidal effect of thienyl 1,3,4-thi(ox)adiazoles and their potential DNA photocleavage. Pest. Biochem. Physiol. 2004, 79: 42-48.

[23] Huang Q*, Wu J, Li X, et al. Toxicity and biochemical action of amicarthiazol on citrus canker pathogen, Xanthomonas citri ex Hasse. Pest. Biochem. Physiol. 2006, 84: 188-195.

[24] Huang Q*,  Kong Y, Liu M, et al. Effect of oxadiazolyl 3(2H)-pyridazinone on the larval growth and digestive physiology of Pseudaletia separata W.  (Lep., Noctuidae).  J. Insect Sci. 2008, 8/19.

[25] Li X, Huang Q*, J. Yuan, et al. Fipronil resistance mechanisms in the rice stem borer Chilo suppressalis Walker. Pest. Biochem. Physiol. 2007, 89: 169-174.

[26] Cao S, Wei N, Zhao C, Li L, Huang Q and Qian X. Syntheses, antifeedant activity, and QSAR analysis of new oxa(thia) diazolyl 3(2H)-pyridazinones. J. Agric. Food Chem. 2005, 53: 3120-3125.

[27] Li G, Qian X, Cui J,Huang Q, Zhang R, Guan H. Syntheses and herbicidal activity of novel 3-amino-carbonyl-2-oxazolidinethione derivatives containing a substituted pyridine ring. J. Agric. Food Chem. 2006, 54: 125-129.

[28] Kong Y, Huang Q*, M. Liu, J. Feng, Y. Liu. Parametric optimization on the sensitive determination of midgut a-amylase in larvae of Mythimna separata Walker. Acta Entomologica Sinica. 2007, 50: 981-988.

[29] Ma Y, Liu R, Gong X, Li Z, Huang Q, Wang H, Song G. Syntheses andherbicidal activity of N,N-diethyl-3-(arylselenonyl)-1H-1,2,4-triazole-1-carboxamide. J. Agric. Food Chem. 2006, 54: 7724-7728.

[30] Tian Z, Shao X, Li Z, Qian X and Huang Q. Syntheses, insecticidal activity and QSAR of novel nitro-methylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification. J. Agric. Food Chem. 2007, 55: 2288-2292. 

[31] Li G, Qian X, Cui J, Huang Q, Cui D, Zhang R, Liu F. Synthesis and herbicidal activities of fluorine-containing 3-pyridylmethyl-2-phenyliminothiazolidine derivatives. J Fluorine Chem 2006, 127: 182-186. 

[32] Cao S, Lu D, Zhao C, Li L, Huang Q and Qian X. An efficient and practical methodfor the synthesis of 1-(2,6-difluorobenzoyl)-3-(2-alkyl-3-oxopyridazin-4-yl)ureas as potential chitin synthesis inhibitors. Monatshefte für Chemie 2006, 137: 779-784. 

[33] Tian Z, Li Z, Huang Q, Xu X, Yu T, Wu Y, Qian X. Synthesis and bioactivities of novel neonicotinoids dioxolane compounds. J Chem Res 2006, 10: 620-622.  

[34] Liu C, Xu X, Li Z, Chen W, Huang Q, Qian X, Synthesis and biological activities of hydroxyl-protected fluorine-containing 4,4-dihydroxyl methyl-2-aryl imino thiazolidines. J Fluorine Chem 2005, 126: 53-58. 

[35] Qian X, Cao S, Li Z, Song G and Huang Q. Oxadiazole derivatives as novel insect-growth regulators: synthesis and structure-bioactivity relationship, in New discoveries in agrochemicals (Eds. J. Marshall Clark and Hideo Ohkawa). American Chemical Society, Washington, DC. 2005, 273-282. 

[36] Huang Q*,  Liu L, Xiao C, Xu Y and Qian X. Photolarvicidal effect of thienyl 1,3,4-thi(ox)adiazoles and their potential DNA photocleavage. Pestic Biochem Physiol 2004, 79, 42-48. 

[37] Liu L, Xu Y, Qian X and Huang Q. Novel analogues of α-terthienyl, thienyl 1,3,4-thia(oxa)diazoles as potential photoactivated insecticides: Synthesis and bioactivity. Chin Chem Let 2004, 15, 7-10. 

[38] Huang Q*,  Qian X, Song G and Cao S. The toxic and antifeedant activity of 2H-pyridazin-3-one-substituted 1,3,4-oxadiazoles against the armyworm Pseudaletia separata Walker and other insects and mites. Pest Manag Sci 2003, 59, 933-939. 

[39] Xu X, Qian X, Li Z, Huang Q and Chen G. Synthesis and insecticidal activity of new substituted N-aryl-N’-benzoylthiourea compounds. J Fluorine Chem 2003, 121: 51-54. 

[40] Zheng X, Li Z, Wang Y, Chen W, Huang Q, Liu C and Song G. Syntheses and insecticidal activities of novel 2,5-disubstituted 1,3,4-oxadiazoles. J Fluorine Chem 2003, 123: 163-169.

  申请发明专利
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用于制备昆虫神经元细胞的生理缓冲液、消解液及方法       201410025109.0

阿维菌素B1a荧光标记物及其应用     201410025107.1

用于检测油菜菌核病菌的方法和培养基     201310564218.5

含七氟异丙基苯甲酰脲类化合物及其用途      CN101538227B

含2’-羟基六氟异丙基的邻苯二甲酰胺类化合物及其用途   CN102320998

新型3-硒代吲哚的合成对植物生长促进和富硒作用   CN101117329B 

含二氟(亚)甲基邻甲酰胺基苯甲酰胺类化合物  公布号：CN 1026 17551 A

具有杀虫活性的含氮杂环化合物、其制备及用途，PCT/CN2008/071115

一类具有高杀虫活性化合物的制备方法及用途，PCT/CN 2006/000360

硝基亚甲基衍生物及其用途，PCT/CN2005/000617，WO05745204.7，US11/751,836，EP1826209A1，JP2007-541642

含硒三唑酰胺类化合物及其制备和应用 - 200310108478.8

一类新型3-硒代吲哚的合成对植物生长促进和富硒作用 - 200610029737. 1

一种噁唑哒嗪及其衍生物的剂型与应用 - 200410017164.1

哌嗪衍生物及其用途 - 200710045661.6

腺苷衍生物及其用途 - 201510022902.X

美国专利 Nitrogenous heterocyclic compounds with insecticidal activity, and the preparation and use thereof    US 12/864,410

PCT专利 Benzoylurea compounds bearing heptafluoroisopropyl and uses thereof     WO/2009/115040 A1